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Compound Detail

CHEMBL510309

BENZO[D]THIAZOLE
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Basic Information

ChEMBL ID CHEMBL510309
Name BENZO[D]THIAZOLE
Phase Preclinical
Structure Type MOL
InChI Key IOJUPLGTWVMSFF-UHFFFAOYSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

135.2
MW (Da)
2.30
ALogP
2
HBA
0
HBD
12.9
PSA (Ų)
0.54
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C7H5NS
MW 135.19
Aromatic Rings 2
Heavy Atoms 9
NP-Likeness -1.93

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
18558667 10.1021/jm701549s No relevant target 2
23750537 10.1021/jm4001488 5'-AMP-activated protein kinase catalytic subunit alpha-2 2
24262887 10.1016/j.bmc.2013.10.037 Indoleamine 2,3-dioxygenase 1 2
19056282 10.1016/j.bmc.2008.11.040 ADMET 1
23750537 10.1021/jm4001488 Unchecked 1
35984756 10.1021/acs.jmedchem.2c00909 HCT-116 1
35984756 10.1021/acs.jmedchem.2c00909 NCI-H522 1

Data from ChEMBL 36 via Core Engine