Compound Detail
CHEMBL51381
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Basic Information
| ChEMBL ID | CHEMBL51381 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UYDRFSXDFIAHHC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
254.3
MW (Da)
3.02
ALogP
3
HBA
1
HBD
55.0
PSA (Ų)
0.72
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.57
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.57 | 7.57 | 27.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 27.0 | nM | 7.57 | In vitro inhibition of [3H]flunitrazepam binding to GABA-A receptor of rat cereb... | 2547070 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2547070 | 10.1021/jm00128a023 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine