Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL51484

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
NC(=O)c1cn(COC(CO)CO)c2ncnc(N)c12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL51484
Phase Preclinical
Structure Type MOL
InChI Key MBEDXJIXQVXSPE-UHFFFAOYSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

281.3
MW (Da)
-1.56
ALogP
8
HBA
4
HBD
149.5
PSA (Ų)
0.50
QED
0
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H15N5O4
MW 281.27
Aromatic Rings 2
Heavy Atoms 20
NP-Likeness 0.05

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
2913300 10.1021/jm00122a019 ADMET 3
2913300 10.1021/jm00122a019 L1210 2
- 10.1016/S0960-894X(00)80470-9 HFF 2
2165163 10.1021/jm00170a019 Human immunodeficiency virus 1
2913300 10.1021/jm00122a019 Human betaherpesvirus 5 1

Data from ChEMBL 36 via Core Engine