Compound Detail
CHEMBL515495
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Basic Information
| ChEMBL ID | CHEMBL515495 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PHSAMILDQDWAIE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
374.4
MW (Da)
4.00
ALogP
3
HBA
2
HBD
73.4
PSA (Ų)
0.71
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.62
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.62 | 4.62 | 24000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 24000.0 | nM | 4.62 | Inhibition Assay: Two-electrode voltage-clamp recordings were made from Xenopus ... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19179076 | 10.1016/j.bmcl.2009.01.005 | Serine/threonine-protein kinase pim-1 | 4 |
Data from ChEMBL 36 via Core Engine