Compound Detail
CHEMBL5170532
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Basic Information
| ChEMBL ID | CHEMBL5170532 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WBSJHGWZDXJNNU-LBPRGKRZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
342.8
MW (Da)
3.28
ALogP
5
HBA
3
HBD
82.9
PSA (Ų)
0.68
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.64
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Serine/threonine-protein kinase PAK 4 CHEMBL4482 | IC50 | 6.64 | 6.64 | 229.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Serine/threonine-protein kinase PAK 4 | IC50 | = | 229.0 | nM | 6.64 | Inhibition of human PAK4 assessed as enzymatic activity incubated for 20 mins by... | 35272236 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35272236 | 10.1016/j.bmc.2022.116700 | Serine/threonine-protein kinase PAK 4 | 2 |
Data from ChEMBL 36 via Core Engine