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Compound Detail

CHEMBL5171831

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CO[C@@]12Cc3ccc(cc3)O[C@H]3[C@@H]4[C@H]5C(=O)[C@](C[C@H](O)OO[C@@]5(C)[C@H]5O[C@@]5(C)[C@H]4[C@]4(C)C[C@H](C)C[C@H](C)[C@@H]34)(C1)C(=O)N2

Basic Information

ChEMBL ID CHEMBL5171831
Phase Preclinical
Structure Type MOL
InChI Key XLNGKUVJTRUXGF-GGGHLTRXSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
11
Publications
0
Known Names

Molecular Properties

581.7
MW (Da)
3.56
ALogP
8
HBA
2
HBD
115.8
PSA (Ų)
0.29
QED
1
Ro5 Violations
1
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C33H43NO8
MW 581.71
Aromatic Rings 1
Heavy Atoms 42
NP-Likeness 2.11

Literature References

PubMed DOI Target Context # Activities
35930265 10.1021/acs.jnatprod.2c00473 Staphylococcus aureus 2
35930265 10.1021/acs.jnatprod.2c00473 Tyrosine-protein phosphatase non-receptor type 6 1
35930265 10.1021/acs.jnatprod.2c00473 Receptor-type tyrosine-protein phosphatase C 1
35930265 10.1021/acs.jnatprod.2c00473 Tyrosine-protein phosphatase non-receptor type 1 1
35930265 10.1021/acs.jnatprod.2c00473 Tyrosine-protein phosphatase non-receptor type 2 1
35930265 10.1021/acs.jnatprod.2c00473 Receptor-type tyrosine-protein phosphatase F 1
35930265 10.1021/acs.jnatprod.2c00473 NCI-H1975 1
35930265 10.1021/acs.jnatprod.2c00473 Bacillus subtilis 1
35930265 10.1021/acs.jnatprod.2c00473 Bacillus amyloliquefaciens 1
35930265 10.1021/acs.jnatprod.2c00473 Escherichia coli 1
35930265 10.1021/acs.jnatprod.2c00473 Streptococcus agalactiae 1

Data from ChEMBL 36 via Core Engine