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Compound Detail

CHEMBL5172662

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COc1cc(C)c(C(=O)O[C@H]2[C@@H](O)[C@@H](O)[C@H](O[C@H]3CC[C@H](C)[C@@H]4[C@@H]3C=C(C)[C@H]3/C(C)=C/CC/C(C)=C/[C@]5(C)C=C(C(=O)O)[C@H](C)C[C@]56OC(=O)C(=C6O)C(=O)[C@@]43C)O[C@@H]2C)c(O)c1

Basic Information

ChEMBL ID CHEMBL5172662
Phase Preclinical
Structure Type MOL
InChI Key FBBPNUSBCOHVCU-MGLSNRCPSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
9
Publications
0
Known Names

Molecular Properties

875.0
MW (Da)
6.75
ALogP
13
HBA
5
HBD
215.6
PSA (Ų)
0.11
QED
3
Ro5 Violations
6
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C49H62O14
MW 875.02
Aromatic Rings 1
Heavy Atoms 63
NP-Likeness 2.06

Literature References

PubMed DOI Target Context # Activities
35640100 10.1021/acs.jnatprod.2c00444 Staphylococcus aureus 3
35640100 10.1021/acs.jnatprod.2c00444 NCI-H460 1
35640100 10.1021/acs.jnatprod.2c00444 SW-620 1
35640100 10.1021/acs.jnatprod.2c00444 Candida albicans 1
35640100 10.1021/acs.jnatprod.2c00444 Escherichia coli 1
35640100 10.1021/acs.jnatprod.2c00444 Mycobacterium tuberculosis variant bovis 1
35640100 10.1021/acs.jnatprod.2c00444 Mycobacterium tuberculosis 1
35640100 10.1021/acs.jnatprod.2c00444 Enterococcus faecalis 1
35640100 10.1021/acs.jnatprod.2c00444 Enterococcus faecium 1

Data from ChEMBL 36 via Core Engine