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Compound Detail

CHEMBL5176703

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C/C=C(/C)C(=O)OC[C@H]1C2=C(C[C@H]3[C@H]4C5=C(C(=O)C(C)=C(OC)C5=O)[C@H](O[C@H]5CC[C@@]6(C)C(=CC[C@H]7C8C[C@H]([C@H](C)CCCC(C)C)C[C@@]8(C)CC[C@@H]76)C5)[C@@H]([C@H](C#N)N13)N4C)C(=O)C(C)=C(OC)C2=O

Basic Information

ChEMBL ID CHEMBL5176703
Phase Preclinical
Structure Type MOL
InChI Key RIQBPMCJZHCTLI-CFTIJBTLSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

960.3
MW (Da)
9.06
ALogP
12
HBA
0
HBD
152.5
PSA (Ų)
0.08
QED
3
Ro5 Violations
12
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C58H77N3O9
MW 960.27
Aromatic Rings 0
Heavy Atoms 70
NP-Likeness 2.14

Literature References

PubMed DOI Target Context # Activities
33333398 10.1016/j.ejmech.2020.113092 HCT-116 1
33333398 10.1016/j.ejmech.2020.113092 QG-56 1
33333398 10.1016/j.ejmech.2020.113092 DU-145 1

Data from ChEMBL 36 via Core Engine