Compound Detail
CHEMBL5182929
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Basic Information
| ChEMBL ID | CHEMBL5182929 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LQBXXGYUJLDSIH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
256.3
MW (Da)
1.55
ALogP
3
HBA
1
HBD
51.1
PSA (Ų)
0.88
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proteasome component C5 CHEMBL4208 | Ki | 7.68 | 7.68 | 21.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proteasome component C5 | Ki | = | 21.0 | nM | 7.68 | Inhibition of human spleen 20S immuno proteosome beta1i subunit assessed as subs... | 34838650 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34838650 | 10.1016/j.bmcl.2021.128478 | Proteasome component C5 | 1 |
Data from ChEMBL 36 via Core Engine