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Compound Detail

CHEMBL5188085

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N[C@@H](Cc1ccc2[nH]c(=O)c(=O)[nH]c2c1)C(=O)O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL5188085
Phase Preclinical
Structure Type MOL
InChI Key CBSWOCDXVMRBEZ-LURJTMIESA-N
0
Targets
2
Activities
2
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

249.2
MW (Da)
-0.83
ALogP
4
HBA
4
HBD
129.0
PSA (Ų)
0.53
QED
0
Ro5 Violations
3
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H11N3O4
MW 249.23
Aromatic Rings 2
Heavy Atoms 18

Activity Summary

IC50 1 meas.
Ki 1 meas.

Literature References

PubMed DOI Target Context # Activities
34998058 10.1016/j.ejmech.2021.114085 Glutamate receptor ionotropic AMPA 3
34998058 10.1016/j.ejmech.2021.114085 Glutamate receptor 2 1
34998058 10.1016/j.ejmech.2021.114085 Glutamate receptor ionotropic, kainate 1 1
34998058 10.1016/j.ejmech.2021.114085 Glutamate receptor ionotropic, kainate 2 1
34998058 10.1016/j.ejmech.2021.114085 Glutamate receptor ionotropic, kainate 3 1

Data from ChEMBL 36 via Core Engine