Compound Detail
CHEMBL5188855
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Basic Information
| ChEMBL ID | CHEMBL5188855 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NTUKIROIQXTDQV-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
423.4
MW (Da)
4.41
ALogP
4
HBA
2
HBD
70.8
PSA (Ų)
0.51
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 8.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 5 CHEMBL1792 | EC50 | 8.7 | 8.68 | 2.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 5 | EC50 | = | 1.995 | nM | 8.7 | Agonist activity at human SST5 expressed in CHO-K1 cells assessed as reduction i... | 35605837 |
| Somatostatin receptor type 5 | EC50 | = | 2.2 | nM | 8.66 | Agonist activity at human SST5 expressed in CHO-K1 cells assessed as reduction i... | 35605837 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 35605837 | 10.1016/j.bmcl.2022.128807 | Somatostatin receptor type 5 | 2 |
Data from ChEMBL 36 via Core Engine