Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5200144

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
N#Cc1ccc(N2CC(CN3CCC(Nc4ncnc5cnc(NC6CC6)cc45)CC3)C2)cc1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL5200144
Phase Preclinical
Structure Type MOL
InChI Key BXOWICWSJYHSBF-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

454.6
MW (Da)
3.48
ALogP
8
HBA
2
HBD
93.0
PSA (Ų)
0.56
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H30N8
MW 454.58
Aromatic Rings 3
Heavy Atoms 34
NP-Likeness -1.59

Literature References

PubMed DOI Target Context # Activities
36173787 10.1021/acs.jmedchem.2c01313 Menin/Histone-lysine N-methyltransferase MLL 1
36173787 10.1021/acs.jmedchem.2c01313 MV4-11 1
36173787 10.1021/acs.jmedchem.2c01313 HL-60 1

Data from ChEMBL 36 via Core Engine