Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5206091

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Cc1c(CO)ncnc1N1CCN(C(=O)[C@H](CNC(C)C)c2ccc(Cl)cc2)CC1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL5206091
Phase Preclinical
Structure Type MOL
InChI Key SIXTXNYBKUMTCG-LJQANCHMSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

432.0
MW (Da)
2.36
ALogP
6
HBA
2
HBD
81.6
PSA (Ų)
0.70
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C22H30ClN5O2
MW 431.97
Aromatic Rings 2
Heavy Atoms 30
NP-Likeness -1.05

Literature References

PubMed DOI Target Context # Activities
35679512 10.1021/acs.jmedchem.2c00527 RAC-alpha serine/threonine-protein kinase 1
35679512 10.1021/acs.jmedchem.2c00527 RAC-beta serine/threonine-protein kinase 1
35679512 10.1021/acs.jmedchem.2c00527 RAC-gamma serine/threonine-protein kinase 1

Data from ChEMBL 36 via Core Engine