Compound Detail
CHEMBL5206855
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5206855 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NIOCXUWXNFYXKC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
474.7
MW (Da)
5.93
ALogP
6
HBA
1
HBD
52.0
PSA (Ų)
0.31
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.15
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transitional endoplasmic reticulum ATPase CHEMBL1075145 | IC50 | 8.15 | 8.15 | 7.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transitional endoplasmic reticulum ATPase | IC50 | = | 7.0 | nM | 8.15 | Inhibition of p97 (unknown origin) in presence of ATP by Biomol Green Reagent ba... | 33873056 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33873056 | 10.1016/j.ejmech.2021.113446 | Transitional endoplasmic reticulum ATPase | 1 |
Data from ChEMBL 36 via Core Engine