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Compound Detail

CHEMBL523126

SECAUBRYENOL
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C=C(CO)[C@@H]1CC[C@H]2[C@]3(CC[C@]4(C)[C@@H]([C@H](C)CCC=C(C)C)CC[C@@]24C)C[C@]13CCC(=O)O

Basic Information

ChEMBL ID CHEMBL523126
Name SECAUBRYENOL
Phase Preclinical
Structure Type MOL
InChI Key JFCYFLMAPFEZKC-XDPIHHSESA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
8
Publications
0
Known Names

Molecular Properties

456.7
MW (Da)
7.40
ALogP
2
HBA
2
HBD
57.5
PSA (Ų)
0.36
QED
1
Ro5 Violations
9
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C30H48O3
MW 456.71
Aromatic Rings 0
Heavy Atoms 33
NP-Likeness 3.35

Literature References

PubMed DOI Target Context # Activities
19456120 10.1021/np900156k NON-PROTEIN TARGET 2
17190447 10.1021/np060273t MCF7 1
17190447 10.1021/np060273t MDA-MB-231 1
17190447 10.1021/np060273t PC-3 1
17190447 10.1021/np060273t HeLa 1
19456120 10.1021/np900156k BT-474 1
19456120 10.1021/np900156k SW-620 1
19456120 10.1021/np900156k HepG2 1

Data from ChEMBL 36 via Core Engine