Compound Detail
CHEMBL5266478
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CO[C@H]1C[C@@H]2CC[C@@H](C)[C@@](O)(O2)C(=O)C(=O)N2CCCC[C@H]2C(=O)O[C@H]([C@H](C)C[C@@H]2CC[C@@H](O)[C@H](OC)C2)CC(=O)[C@H](C)/C=C(\C)[C@@H](O)[C@@H](OC)C(=O)[C@H](C)C[C@H](C)C2C=CC(/C=C/1C)ON2c1ccccc1
Basic Information
| ChEMBL ID | CHEMBL5266478 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JFCJJEJRERDVOZ-SRPGMSAOSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1021.3
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 6.38
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cortical neurone CHEMBL5314313 | EC50 | 6.38 | 6.27 | 420.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cortical neurone | EC50 | = | 420.0 | nM | 6.38 | Neuroprotective activity in rat Primary cortical neuron assessed as increase in ... | 32966896 |
| Cortical neurone | EC50 | = | 700.0 | nM | 6.16 | Neuroprotective activity in rat Primary cortical neuron assessed as increase in ... | 32966896 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 32966896 | 10.1016/j.ejmech.2020.112820 | Cortical neurone | 2 |
Data from ChEMBL 36 via Core Engine