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Compound Detail

CHEMBL5266503

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N#Cc1cc(-c2ccc(N)nc2)cnc1Cl

Basic Information

ChEMBL ID CHEMBL5266503
Phase Preclinical
Structure Type MOL
InChI Key HOTVBPKZXBNYFL-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

230.7
MW (Da)
2.25
ALogP
4
HBA
1
HBD
75.6
PSA (Ų)
0.76
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H7ClN4
MW 230.66
Aromatic Rings 2
Heavy Atoms 16
NP-Likeness -0.64

Literature References

PubMed DOI Target Context # Activities
36706844 10.1016/j.bmcl.2023.129152 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 1

Data from ChEMBL 36 via Core Engine