Compound Detail
CHEMBL5266600
ROSOLUTAMIDE 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL5266600 |
| Name | ROSOLUTAMIDE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | PJOSHEDKRPRCAE-QHKWOANTSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
4
Known Names
Molecular Properties
464.6
MW (Da)
5.39
ALogP
6
HBA
0
HBD
71.1
PSA (Ų)
0.31
QED
1
Ro5 Violations
12
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Achiral |
Activity Summary
IC50 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glioblastoma cell line CHEMBL614503 | IC50 | 5.7 | 5.7 | 2000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glioblastoma cell line | IC50 | = | 2000.0 | nM | 5.7 | Induction of ferroptosis in human primary glioblastoma cells assessed as decreas... | 36332549 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36332549 | 10.1016/j.ejmech.2022.114861 | Unchecked | 1 |
| 36332549 | 10.1016/j.ejmech.2022.114861 | Glioblastoma cell line | 1 |
Data from ChEMBL 36 via Core Engine