Compound Detail
CHEMBL5269050
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Basic Information
| ChEMBL ID | CHEMBL5269050 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WSQZYRFZGIBJJU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
324.8
MW (Da)
4.09
ALogP
5
HBA
2
HBD
59.1
PSA (Ų)
0.84
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| BCL-6/NCOR2 CHEMBL4523673 | IC50 | 4.72 | 4.72 | 19000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| BCL-6/NCOR2 | IC50 | = | 19000.0 | nM | 4.72 | Inhibition of BCL6/SMRT protein protein interaction (unknown origin) by TR-FRET ... | 33844535 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 33844535 | 10.1021/acs.jmedchem.0c01686 | BCL-6/NCOR2 | 1 |
Data from ChEMBL 36 via Core Engine