Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5269734

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Cc1cc2c(ccn2-c2c(Cl)cc(-n3nc(C#N)c(=O)[nH]c3=O)cc2Cl)cc1O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL5269734
Phase Preclinical
Structure Type MOL
InChI Key GQJZOTUABXERSK-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

428.2
MW (Da)
3.06
ALogP
7
HBA
2
HBD
116.7
PSA (Ų)
0.51
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C19H11Cl2N5O3
MW 428.24
Aromatic Rings 4
Heavy Atoms 29
NP-Likeness -1.01

Literature References

PubMed DOI Target Context # Activities
36799411 10.1021/acs.jmedchem.2c01669 Thyroid hormone receptor alpha 1
36799411 10.1021/acs.jmedchem.2c01669 Thyroid hormone receptor beta 1
36799411 10.1021/acs.jmedchem.2c01669 Unchecked 1

Data from ChEMBL 36 via Core Engine