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Compound Detail

CHEMBL5274405

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COc1ccc2ccc3ccc(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)c(O)c3c2c1

Basic Information

ChEMBL ID CHEMBL5274405
Phase Preclinical
Structure Type MOL
InChI Key KOVHBFHRGDLMAS-CMWLGVBASA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

402.4
MW (Da)
0.89
ALogP
8
HBA
5
HBD
128.8
PSA (Ų)
0.41
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C21H22O8
MW 402.40
Aromatic Rings 3
Heavy Atoms 29
NP-Likeness 1.57

Activity Summary

IC50 1 meas. best 6.7

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
No relevant target
CHEMBL2362975
IC50 6.7 6.7 200.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
No relevant target IC50 = 200.0 nM 6.7 Antioxidant activity assessed as DPPH radical scavenging activity 29280630

Literature References

PubMed DOI Target Context # Activities
29280630 10.1021/acs.jnatprod.7b00619 BV-2 1
29280630 10.1021/acs.jnatprod.7b00619 No relevant target 1

Data from ChEMBL 36 via Core Engine