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Compound Detail

CHEMBL5278897

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OC[C@@H]1[C@@H](O)[C@H](O)[C@H]2[C@@H](O)C(F)(F)CN21
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL5278897
Phase Preclinical
Structure Type MOL
InChI Key SITWLQWCPGXKDE-IECVIRLLSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

225.2
MW (Da)
-2.24
ALogP
5
HBA
4
HBD
84.2
PSA (Ų)
0.41
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C8H13F2NO4
MW 225.19
Aromatic Rings 0
Heavy Atoms 15
NP-Likeness 1.43

Activity Summary

IC50 2 meas.

Literature References

PubMed DOI Target Context # Activities
36332547 10.1016/j.ejmech.2022.114852 Unchecked 12
36332547 10.1016/j.ejmech.2022.114852 Alpha-glucosidase 1
36332547 10.1016/j.ejmech.2022.114852 Alpha-mannosidase 1
36332547 10.1016/j.ejmech.2022.114852 Alpha-galactosidase 1
36332547 10.1016/j.ejmech.2022.114852 Tissue alpha-L-fucosidase 1

Data from ChEMBL 36 via Core Engine