Compound Detail
CHEMBL5281090
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Basic Information
| ChEMBL ID | CHEMBL5281090 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AUQAPKZQZHCYIW-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
356.4
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leishmania major CHEMBL612879 | IC50 | 7.52 | 7.52 | 30.1 | 1 |
| Leishmania amazonensis CHEMBL612877 | IC50 | 6.55 | 6.55 | 280.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leishmania major | IC50 | = | 30.1 | nM | 7.52 | Antibacterial activity against Leishmania major assessed as bacterial growth inh... | 34217061 |
| Leishmania amazonensis | IC50 | = | 280.0 | nM | 6.55 | Antibacterial activity against Leishmania amazonensis assessed as bacterial grow... | 34217061 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34217061 | 10.1016/j.ejmech.2021.113621 | Leishmania major | 1 |
| 34217061 | 10.1016/j.ejmech.2021.113621 | Leishmania amazonensis | 1 |
Data from ChEMBL 36 via Core Engine