Compound Detail
CHEMBL5281769
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Basic Information
| ChEMBL ID | CHEMBL5281769 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PZHKTUVCRZTDBK-FYTLMZHYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
173.0
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Arginase-1 CHEMBL3232699 | IC50 | 4.82 | 4.82 | 15000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Arginase-1 | IC50 | = | 15000.0 | nM | 4.82 | Inhibition of rat liver arginase using L-arginine as substrate incubated for 10 ... | 34875836 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34875836 | 10.1021/acs.jmedchem.1c01691 | Arginase-1 | 1 |
Data from ChEMBL 36 via Core Engine