Compound Detail
CHEMBL5283816
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Basic Information
| ChEMBL ID | CHEMBL5283816 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZRHUJXRVIMMHFG-ZDUSSCGKSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
317.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.29
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 7.29 | 6.49 | 51.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 51.0 | nM | 7.29 | Inhibition of Escherichia coli VIM-2 | 34875836 |
| Unchecked | IC50 | = | 2040.0 | nM | 5.69 | Inhibition of Escherichia coli NDM-1 | 34875836 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34875836 | 10.1021/acs.jmedchem.1c01691 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine