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Compound Detail

CHEMBL5287442

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COc1cc(O)c(-c2cc3c(cc2O)CCc2cc(OC)cc(O)c2-3)c(CCc2cccc(O)c2)c1

Basic Information

ChEMBL ID CHEMBL5287442
Phase Preclinical
Structure Type MOL
InChI Key OBMLMLMDXBKLSM-UHFFFAOYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

484.6
MW (Da)
5.74
ALogP
6
HBA
4
HBD
99.4
PSA (Ų)
0.28
QED
1
Ro5 Violations
6
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C30H28O6
MW 484.55
Aromatic Rings 4
Heavy Atoms 36
NP-Likeness 0.91

Activity Summary

EC50 1 meas. best 4.25

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
No relevant target
CHEMBL2362975
EC50 4.25 4.25 55900.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
No relevant target EC50 = 55900.0 nM 4.25 Antioxidant activity assessed as DPPH radical scavenging activity 29280630

Literature References

PubMed DOI Target Context # Activities
29280630 10.1021/acs.jnatprod.7b00619 No relevant target 1

Data from ChEMBL 36 via Core Engine