Compound Detail
CHEMBL5287570
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Basic Information
| ChEMBL ID | CHEMBL5287570 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PRONDDAHUBCYBW-YFKPBYRVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
210.2
MW (Da)
-1.14
ALogP
4
HBA
3
HBD
123.5
PSA (Ų)
0.48
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 4.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Arginase-1 CHEMBL1075060 | Ki | 4.05 | 4.05 | 90000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Arginase-1 | Ki | = | 90000.0 | nM | 4.05 | Binding affinity to bovine liver Arg I | 34875836 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 34875836 | 10.1021/acs.jmedchem.1c01691 | Arginase-1 | 1 |
Data from ChEMBL 36 via Core Engine