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Compound Detail

CHEMBL53588

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COCC1=C(N)C(=O)C2=C(C1=O)N1C[C@H]3[C@H](N3C)[C@]1(O)[C@H]2COC(N)=O

Basic Information

ChEMBL ID CHEMBL53588
Phase Preclinical
Structure Type MOL
InChI Key YMGWZHNOYQVRLT-UMNDVAMSSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

364.4
MW (Da)
-2.34
ALogP
9
HBA
3
HBD
148.2
PSA (Ų)
0.37
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H20N4O6
MW 364.36
Aromatic Rings 0
Heavy Atoms 26
NP-Likeness 1.17

Literature References

PubMed DOI Target Context # Activities
8021918 10.1021/jm00038a008 HeLa 1

Data from ChEMBL 36 via Core Engine