Compound Detail
CHEMBL5394678
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Basic Information
| ChEMBL ID | CHEMBL5394678 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IJOSHLQCVXEGBP-UHFFFAOYSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
224.2
MW (Da)
0.48
ALogP
5
HBA
2
HBD
75.1
PSA (Ų)
0.64
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.66
IC50 1 meas. best 6.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tripartite terminase subunit 3 CHEMBL4879551 | IC50 | 6.66 | 6.66 | 220.0 | 1 |
| Cytomegalovirus CHEMBL613134 | EC50 | 6.66 | 6.66 | 220.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cytomegalovirus | EC50 | = | 220.0 | nM | 6.66 | Antiviral activity against Human Cytomegalovirus | 37827528 |
| Tripartite terminase subunit 3 | IC50 | = | 220.0 | nM | 6.66 | Inhibition of Human Cytomegalovirus C-terminal UL89 phosphorylation using (5-tcg... | 37827528 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37827528 | 10.1021/acs.jmedchem.3c01280 | Cytomegalovirus | 2 |
| 37827528 | 10.1021/acs.jmedchem.3c01280 | ADMET | 1 |
| 37827528 | 10.1021/acs.jmedchem.3c01280 | Tripartite terminase subunit 3 | 1 |
Data from ChEMBL 36 via Core Engine