Compound Detail
CHEMBL5399549
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Basic Information
| ChEMBL ID | CHEMBL5399549 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LFKXUURWUQGRKZ-GOSISDBHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
334.5
MW (Da)
4.70
ALogP
3
HBA
0
HBD
17.4
PSA (Ų)
0.65
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 8.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cortical neurone CHEMBL5314313 | EC50 | 8.0 | 8.0 | 10.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cortical neurone | EC50 | = | 10.0 | nM | 8.0 | Induction of neurite outgrowth in Wistar rat Cortical neuron cells assessed as i... | 37736170 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37736170 | 10.1021/acsmedchemlett.3c00309 | Cortical neurone | 3 |
Data from ChEMBL 36 via Core Engine