Compound Detail
CHEMBL5401057
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Basic Information
| ChEMBL ID | CHEMBL5401057 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RKGVDNNTAXKCNU-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
406.5
MW (Da)
5.79
ALogP
4
HBA
1
HBD
55.1
PSA (Ų)
0.41
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.94
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| GL261 CHEMBL4483239 | IC50 | 4.94 | 4.94 | 11440.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| GL261 | IC50 | = | 11440.0 | nM | 4.94 | Anti-proliferative activity against mouse GL261 cells assessed as cell viability... | 37861443 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37861443 | 10.1021/acs.jmedchem.3c01090 | U-87 MG | 1 |
| 37861443 | 10.1021/acs.jmedchem.3c01090 | GL261 | 1 |
Data from ChEMBL 36 via Core Engine