Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5401983

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Cc1nn(CCCCCCn2nc(C)c(Cl)c2C)c(C)c1Cl
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL5401983
Phase Preclinical
Structure Type MOL
InChI Key CKZPGTULVZDCJD-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

343.3
MW (Da)
4.88
ALogP
4
HBA
0
HBD
35.6
PSA (Ų)
0.67
QED
0
Ro5 Violations
7
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H24Cl2N4
MW 343.30
Aromatic Rings 2
Heavy Atoms 22
NP-Likeness -1.24

Literature References

PubMed DOI Target Context # Activities
37465295 10.1021/acsmedchemlett.2c00470 Unchecked 1
37465295 10.1021/acsmedchemlett.2c00470 Glutaminase kidney isoform, mitochondrial 1
37465295 10.1021/acsmedchemlett.2c00470 Thioredoxin reductase 1
37465295 10.1021/acsmedchemlett.2c00470 H22 1
37465295 10.1021/acsmedchemlett.2c00470 A549 1

Data from ChEMBL 36 via Core Engine