Compound Detail
CHEMBL540427
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Basic Information
| ChEMBL ID | CHEMBL540427 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UYSNCZHSYFZFQK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
263.7
MW (Da)
2.39
ALogP
4
HBA
1
HBD
64.1
PSA (Ų)
0.92
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 CHEMBL2736 | EC50 | 5.19 | 5.19 | 6400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Metabotropic glutamate receptor 4 | EC50 | = | 6400.0 | nM | 5.19 | PUBCHEM_BIOASSAY: Modulation of the Metabotropic Glutamate Receptor mGluR4: Calc... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19469556 | 10.1021/jm9005065 | Metabotropic glutamate receptor 4 | 6 |
Data from ChEMBL 36 via Core Engine