Compound Detail
CHEMBL5404734
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Basic Information
| ChEMBL ID | CHEMBL5404734 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OWKBIFBFJMCFFF-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
462.5
MW (Da)
5.99
ALogP
6
HBA
1
HBD
78.3
PSA (Ų)
0.32
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Estrogen-related receptor gamma CHEMBL3585238 | IC50 | 5.68 | 5.68 | 2110.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Estrogen-related receptor gamma | IC50 | = | 2110.0 | nM | 5.68 | Inverse agonist activity at Gal4-tagged mouse ERR-gamma LBD transfected in HEK29... | 36805944 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36805944 | 10.1016/j.ejmech.2023.115174 | Estrogen-related receptor gamma | 1 |
Data from ChEMBL 36 via Core Engine