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Compound Detail

CHEMBL54049

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CC(C)c1cccc(C(=O)O)c1O

Basic Information

ChEMBL ID CHEMBL54049
Phase Preclinical
Structure Type MOL
InChI Key XGAYQDWZIPRBPF-UHFFFAOYSA-N
0
Targets
3
Activities
1
Assay Types
0
PK Parameters
12
Publications
0
Known Names

Molecular Properties

180.2
MW (Da)
2.21
ALogP
2
HBA
2
HBD
57.5
PSA (Ų)
0.73
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H12O3
MW 180.20
Aromatic Rings 1
Heavy Atoms 13
NP-Likeness 0.32

Activity Summary

EC50 3 meas.

Literature References

PubMed DOI Target Context # Activities
12109905 10.1021/jm010461a GABA-A receptor; alpha-1/beta-2/gamma-2 2
12109905 10.1021/jm010461a Xenopus laevis 1
12109905 10.1021/jm010461a No relevant target 1
9599235 10.1021/jm970681h GABA-A receptor; anion channel 1
21189019 10.1021/jm101266s Stromelysin-1 1
21189019 10.1021/jm101266s Polyunsaturated fatty acid 5-lipoxygenase 1
21189019 10.1021/jm101266s Interstitial collagenase 1
21189019 10.1021/jm101266s Neutrophil collagenase 1
21189019 10.1021/jm101266s Matrix metalloproteinase-9 1
21189019 10.1021/jm101266s Lethal factor 1
21189019 10.1021/jm101266s Tyrosinase 1
21189019 10.1021/jm101266s 72 kDa type IV collagenase 1

Data from ChEMBL 36 via Core Engine