Compound Detail
CHEMBL5405358
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5405358 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WHGFEYAZNDVANN-JTQLQIEISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
297.1
MW (Da)
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.91
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 20S proteasome CHEMBL3831201 | IC50 | 6.91 | 6.91 | 124.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 20S proteasome | IC50 | = | 124.2 | nM | 6.91 | Inhibition of human 20S proteasome chymotrypsin-like activity using Suc-Leu-Leu-... | 36806958 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36806958 | 10.1016/j.ejmech.2023.115187 | 20S proteasome | 1 |
Data from ChEMBL 36 via Core Engine