Compound Detail
CHEMBL5413030
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Basic Information
| ChEMBL ID | CHEMBL5413030 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | MKOBWNOQMYPNPP-WMCAAGNKSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
363.5
MW (Da)
2.69
ALogP
7
HBA
3
HBD
93.7
PSA (Ų)
0.60
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 8.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RNA 5'-monophosphate methyltransferase CHEMBL3588740 | IC50 | 8.21 | 7.78 | 6.1 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RNA 5'-monophosphate methyltransferase | IC50 | = | 6.1 | nM | 8.21 | Inhibition of BCDIN3D (unknown origin) using mini-helix and SAM as substrate inc... | - |
| RNA 5'-monophosphate methyltransferase | IC50 | = | 44.4 | nM | 7.35 | Binding affinity towards N-terminal ePL-tagged BCDIN3D (unknown origin) transfec... | - |
Data from ChEMBL 36 via Core Engine