Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5418432

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
O=C(c1cccc(CNc2n[nH]c3c(Cl)cc([N+](=O)[O-])cc23)c1)N1CCN(C(=O)c2ccc(Cl)cc2Cl)CC1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL5418432
Phase Preclinical
Structure Type MOL
InChI Key USOSQTLRHGHAMV-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

587.9
MW (Da)
5.64
ALogP
6
HBA
2
HBD
124.5
PSA (Ų)
0.22
QED
2
Ro5 Violations
6
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C26H21Cl3N6O4
MW 587.85
Aromatic Rings 4
Heavy Atoms 39
NP-Likeness -1.64

Literature References

PubMed DOI Target Context # Activities
36649216 10.1021/acs.jmedchem.2c01410 Mitogen-activated protein kinase 8 1
36649216 10.1021/acs.jmedchem.2c01410 Mitogen-activated protein kinase 10 1

Data from ChEMBL 36 via Core Engine