Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5420268

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
C[C@@H](O)[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CS)NC(=O)CN)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)c(I)c1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

Basic Information

ChEMBL ID CHEMBL5420268
Phase Preclinical
Structure Type MOL
InChI Key NXNBLYISDGDSIN-ULYLZKHVSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names

Molecular Properties

1693.7
MW (Da)

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C62H93IN20O20S4
MW 1693.72

Activity Summary

IC50 2 meas. best 9.05

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Nicotinic acetylcholine receptor alpha9/alpha10
CHEMBL3038462
IC50 9.05 9.05 0.9 1
Neuronal acetylcholine receptor; alpha9/alpha10
CHEMBL2109238
IC50 8.82 8.82 1.5 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
37464764 10.1021/acs.jmedchem.3c01023 Nicotinic acetylcholine receptor alpha9/alpha10 1
37464764 10.1021/acs.jmedchem.3c01023 Neuronal acetylcholine receptor; alpha9/alpha10 1
37464764 10.1021/acs.jmedchem.3c01023 Unchecked 1

Data from ChEMBL 36 via Core Engine