Compound Detail
CHEMBL5424801
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COc1ccc(-c2ccc3c(c2)-n2c(nnc2-c2ccc(N4CCNCC4)c(C(F)(F)F)c2)CC(=O)N3)cn1
Basic Information
| ChEMBL ID | CHEMBL5424801 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PTKYEQBTNBDEQV-UHFFFAOYSA-N |
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
10
Publications
0
Known Names
Molecular Properties
535.5
MW (Da)
3.93
ALogP
8
HBA
2
HBD
97.2
PSA (Ų)
0.41
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 37859717 | 10.1039/d3md00209h | No relevant target | 4 |
| 37859717 | 10.1039/d3md00209h | Serine/threonine-protein kinase RIO2 | 1 |
| 37859717 | 10.1039/d3md00209h | Tyrosine-protein kinase ABL1 | 1 |
| 37859717 | 10.1039/d3md00209h | Proto-oncogene tyrosine-protein kinase receptor Ret | 1 |
| 37859717 | 10.1039/d3md00209h | Fibroblast growth factor receptor 1 | 1 |
| 37859717 | 10.1039/d3md00209h | Receptor-type tyrosine-protein kinase FLT3 | 1 |
| 37859717 | 10.1039/d3md00209h | Fibroblast growth factor receptor 2 | 1 |
| 37859717 | 10.1039/d3md00209h | U-87 MG | 1 |
| 37859717 | 10.1039/d3md00209h | MKN-1 | 1 |
| 37859717 | 10.1039/d3md00209h | MOLT-4 | 1 |
Data from ChEMBL 36 via Core Engine