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Compound Detail

CHEMBL543

1-METHYLIMIDAZOLE
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Basic Information

ChEMBL ID CHEMBL543
Name 1-METHYLIMIDAZOLE
Phase Preclinical
Structure Type MOL
InChI Key MCTWTZJPVLRJOU-UHFFFAOYSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
15
Publications
0
Known Names

Molecular Properties

82.1
MW (Da)
0.42
ALogP
2
HBA
0
HBD
17.8
PSA (Ų)
0.44
QED
0
Ro5 Violations
0
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C4H6N2
MW 82.11
Aromatic Rings 1
Heavy Atoms 6
NP-Likeness -1.42

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
4020834 10.1021/jm00146a028 Epoxide hydrolase 1 2
- 10.6019/CHEMBL4495565 SARS-CoV-2 2
8667357 10.1021/jm950589q No relevant target 1
4020834 10.1021/jm00146a028 Unchecked 1
4020834 10.1021/jm00146a028 No relevant target 1
2066976 10.1021/jm00111a020 No relevant target 1
- 10.1016/0960-894X(95)00136-H No relevant target 1
9435905 10.1021/jm970488n No relevant target 1
7381846 10.1021/jm00179a001 Staphylococcus aureus 1
7381846 10.1021/jm00179a001 Pseudomonas aeruginosa 1
7381846 10.1021/jm00179a001 Streptococcus pyogenes 1
19128860 10.1016/j.ejmech.2008.12.004 Cytochrome P450 3A4 1
17417631 10.1038/nchembio873 Unchecked 1
114658 10.1021/jm00195a026 No relevant target 1
- 10.6019/CHEMBL4495564 Replicase polyprotein 1ab 1

Data from ChEMBL 36 via Core Engine