Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL5430452

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
Cc1cccc2c(NCc3cccc(C(=O)N4CCN(C(=O)c5ccc(Cl)cc5Cl)CC4)c3)n[nH]c12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL5430452
Phase Preclinical
Structure Type MOL
InChI Key USMQZGFJRJOXOJ-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

522.4
MW (Da)
5.39
ALogP
4
HBA
2
HBD
81.3
PSA (Ų)
0.37
QED
2
Ro5 Violations
5
Rot. Bonds

Drug Information

Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C27H25Cl2N5O2
MW 522.44
Aromatic Rings 4
Heavy Atoms 36
NP-Likeness -1.49

Literature References

PubMed DOI Target Context # Activities
36649216 10.1021/acs.jmedchem.2c01410 Mitogen-activated protein kinase 8 1
36649216 10.1021/acs.jmedchem.2c01410 Mitogen-activated protein kinase 10 1

Data from ChEMBL 36 via Core Engine