Compound Detail
CHEMBL5433870
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Basic Information
| ChEMBL ID | CHEMBL5433870 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IBMWMXLKRQTPOA-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names
Molecular Properties
330.9
MW (Da)
5.17
ALogP
2
HBA
2
HBD
58.9
PSA (Ų)
0.60
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Bromodomain-containing protein 9 CHEMBL3108640 | Kd | 6.1 | 6.1 | 800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Bromodomain-containing protein 9 | Kd | = | 800.0 | nM | 6.1 | Binding affinity to BRD9 (unknown origin) assessed as dissociation constant by s... | 36736153 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 36736153 | 10.1016/j.ejmech.2023.115139 | Unchecked | 6 |
| 36736153 | 10.1016/j.ejmech.2023.115139 | Bromodomain-containing protein 4 | 1 |
| 36736153 | 10.1016/j.ejmech.2023.115139 | CREB-binding protein | 1 |
| 36736153 | 10.1016/j.ejmech.2023.115139 | Bromodomain-containing protein 7 | 1 |
| 36736153 | 10.1016/j.ejmech.2023.115139 | Bromodomain-containing protein 9 | 1 |
| 36736153 | 10.1016/j.ejmech.2023.115139 | Bromodomain testis-specific protein | 1 |
| 36736153 | 10.1016/j.ejmech.2023.115139 | Chromatin remodeling regulator CECR2 | 1 |
Data from ChEMBL 36 via Core Engine