Compound Detail
CHEMBL546751
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Basic Information
| ChEMBL ID | CHEMBL546751 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UTXULAAHKMRIJF-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
266.3
MW (Da)
2.96
ALogP
5
HBA
2
HBD
73.1
PSA (Ų)
0.76
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 5.4 | 5.31 | 4020.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 4020.0 | nM | 5.4 | Inhibition of RML prion protein infected in mouse dividing ScN2a-cl3 cells expre... | 24183589 |
| Unchecked | EC50 | = | 5990.0 | nM | 5.22 | Inhibition of RML prion protein infected in mouse dividing ScN2a-cl3 cells expre... | 24183589 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24183589 | 10.1016/j.bmc.2013.09.022 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine