Compound Detail
CHEMBL550238
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
C=COC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)CNC(=O)OCc1ccccc1)C(C)C
Basic Information
| ChEMBL ID | CHEMBL550238 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | BHCUJWBXHYNINM-ONTIZHBOSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
534.6
MW (Da)
0.75
ALogP
8
HBA
5
HBD
172.2
PSA (Ų)
0.16
QED
1
Ro5 Violations
15
Rot. Bonds
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.54
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.54 | 5.54 | 2890.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2890.0 | nM | 5.54 | Inhibition of post acidic activity of proteasome from human PBMC after 30 mins b... | 19577931 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19577931 | 10.1016/j.bmc.2009.06.025 | Unchecked | 6 |
Data from ChEMBL 36 via Core Engine