Compound Detail
CHEMBL553423
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Basic Information
| ChEMBL ID | CHEMBL553423 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CIIDBUDXODMZQH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
343.3
MW (Da)
4.11
ALogP
3
HBA
3
HBD
64.6
PSA (Ų)
0.42
QED
0
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H4 receptor CHEMBL3759 | Ki | 8.8 | 8.8 | 1.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H4 receptor | Ki | = | 1.585 | nM | 8.8 | Agonistic activity at histamine H4 receptor | 21348462 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21348462 | 10.1021/jm1013488 | Histamine H4 receptor | 1 |
| 21348462 | 10.1021/jm1013488 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine