Compound Detail
CHEMBL5537041
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL5537041 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YONGTGKRCXENMP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
355.4
MW (Da)
4.92
ALogP
3
HBA
0
HBD
31.2
PSA (Ų)
0.51
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.66 | 5.66 | 2180.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2180.0 | nM | 5.66 | Inhibition of HIF-1 (unknown origin) expressed in MH7A cells cotransfected with ... | 38688063 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38688063 | 10.1016/j.ejmech.2024.116417 | Unchecked | 3 |
Data from ChEMBL 36 via Core Engine