Compound Detail
CHEMBL554783
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL554783 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CHYKGAOLCGVTFR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
345.2
MW (Da)
2.97
ALogP
6
HBA
0
HBD
69.7
PSA (Ų)
0.80
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Macrophage migration inhibitory factor CHEMBL2085 | IC50 | 4.26 | 4.26 | 55000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Macrophage migration inhibitory factor | IC50 | = | 55000.0 | nM | 4.26 | Inhibition of dopachrome tautomerase activity of human recombinant MIF | 19592246 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19592246 | 10.1016/j.bmcl.2009.06.052 | Macrophage migration inhibitory factor | 2 |
Data from ChEMBL 36 via Core Engine