Compound Detail
CHEMBL5555854
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Basic Information
| ChEMBL ID | CHEMBL5555854 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GGLWIFQUSKWUCW-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
328.4
MW (Da)
2.64
ALogP
4
HBA
2
HBD
88.5
PSA (Ų)
0.78
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 2 meas. best 5.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Probable G-protein coupled receptor 132 CHEMBL3085618 | EC50 | 5.16 | 5.16 | 6870.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Probable G-protein coupled receptor 132 | EC50 | = | 6870.0 | nM | 5.16 | Agonist activity at human G2A expressed in CHO-K1 cells co-expressing human GNA1... | 38917049 |
| Probable G-protein coupled receptor 132 | EC50 | = | 6918.31 | nM | 5.16 | Agonist activity at human G2A expressed in CHO-K1 cells co-expressing human GNA1... | 38917049 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38917049 | 10.1021/acs.jmedchem.3c02164 | Probable G-protein coupled receptor 132 | 3 |
| 38917049 | 10.1021/acs.jmedchem.3c02164 | Guanine nucleotide-binding protein subunit alpha-11 | 1 |
Data from ChEMBL 36 via Core Engine