Compound Detail
CHEMBL5556193
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Basic Information
| ChEMBL ID | CHEMBL5556193 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VAGRKWNZVMXJPW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
405.2
MW (Da)
3.14
ALogP
3
HBA
1
HBD
66.5
PSA (Ų)
0.80
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ubiquitin carboxyl-terminal hydrolase 2 CHEMBL1293227 | IC50 | 6.6 | 6.6 | 250.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ubiquitin carboxyl-terminal hydrolase 2 | IC50 | = | 250.0 | nM | 6.6 | Inhibition of USP2 (unknown origin) incubated for 20 mins followed by substrate ... | 38452725 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 38452725 | 10.1016/j.ejmech.2024.116275 | Ubiquitin carboxyl-terminal hydrolase 2 | 1 |
Data from ChEMBL 36 via Core Engine